Identification of cancer-specific cell surface targets for CAR-T cell therapy
Abstract One should identify appropriate cell surface targets to develop new CAR-T cells. Currently, lineage-specific antigens such as CD19 or B cell maturation antigen (BCMA) are being used as targets for CAR-T cells. However, in most cancers, lineage-specific antigens cannot be used as targets bec...
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BMC,
2024-03-01T00:00:00Z.
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