DMSO-tolerant ornithine decarboxylase (ODC) tandem assay optimised for high-throughput screening

Ornithine decarboxylase (ODC), the first rate-limiting enzyme in polyamine synthesis, has emerged as a therapeutic target for cancer and Alzheimer's disease (AD). To inhibit ODC, α-difluoromethylornithine (DFMO), an irreversible ODC inhibitor, has been widely used. However, due to its poor phar...

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Bibliographic Details
Main Authors: Mingu Gordon Park (Author), Suyeon Yellena Kim (Author), C. Justin Lee (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available