Immunogenic Cell Death Enhances Immunotherapy of Diffuse Intrinsic Pontine Glioma: From Preclinical to Clinical Studies

• Main Authors: Guohao Liu (Author), Yanmei Qiu (Author), Po Zhang (Author), Zirong Chen (Author), Sui Chen (Author), Weida Huang (Author), Baofeng Wang (Author), Xingjiang Yu (Author), Dongsheng Guo (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diffuse intrinsic pontine glioma (DIPG) is the most lethal tumor involving the pediatric central nervous system. The median survival of children that are diagnosed with DIPG is only 9 to 11 months. More than 200 clinical trials have failed to increase the survival outcomes using conventional cytotox...