Genetic variants in LGALS3 are related to lower galectin-3 serum levels and clinical outcomes in systemic sclerosis patients: A case-control study

• প্রধান লেখক: Eudes Gustavo Constantino Cunha (লেখক), Camilla Albertina Dantas de Lima (লেখক), Kamila de Melo Vilar (লেখক), Marcelo Francisco de Nóbrega (লেখক), Anderson Rodrigues de Almeida (লেখক), Michelly Cristiny Pereira (লেখক), Andréa Tavares Dantas (লেখক), Rafaela Silva Guimarães Gonçalves (লেখক), Moacyr Jesus Barreto de Melo Rêgo (লেখক), Angela Luzia Branco Pinto Duarte (লেখক), Maira Galdino da Rocha Pitta (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2021-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Introduction Systemic sclerosis (SSc) is a rare complex disease characterized by vascular damage, autoimmunity, and extensive skin and internal organs fibrosis. Galectin-3 (Gal-3) is encoded by gene LGALS3 (Lectin, Galactoside-Binding, Soluble, 3; 14q22.3) and it has been reported to play a central...