Extracellular vesicles from synovial fluid-derived mesenchymal stem cells confer chondroprotective effects on in vitro and in vivo osteoarthritic chondrocytes

• Hoofdauteurs: Haixiang Liang (Auteur), Dan Li (Auteur), Eric V. Neufeld (Auteur), Michael J. Sayegh (Auteur), Adam Kiridly (Auteur), Pablo Palacios (Auteur), Henintsoa Fanjaniaina Andriamifidy (Auteur), Pooja Swami (Auteur), Kenneth R. Zaslav (Auteur), Nicholas A. Sgaglione (Auteur), Daniel A. Grande (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2023-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Introduction: Extracellular vesicles (EVs) released by mesenchymal stem cells (MSCs) are theorized to mediate cartilage regeneration through paracrine actions. It is hypothesized that EVs derived from synovial fluid MSCs (SF-MSCs) will promote anabolic gene expressions and decrease catabolic markers...