Ethyl pyruvate protects against sepsis-associated encephalopathy through inhibiting the NLRP3 inflammasome

• Main Authors: Xiaoli Zhong (Author), Lingli Xie (Author), Xiaolong Yang (Author), Fang Liang (Author), Yanliang Yang (Author), Jianbin Tong (Author), Yanjun Zhong (Author), Kai Zhao (Author), Yiting Tang (Author), Chuang Yuan (Author)
• Format: Book
• Published: BMC, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background With the advance of antibiotics and life support therapy, the mortality of sepsis has been decreasing in recent years. However, the incidence of sepsis-associated encephalopathy (SAE), a common complication of sepsis, is still high. There are few effective therapies to treat clin...