The Employment of Leukotriene Antagonists in Cutaneous Diseases Belonging to Allergological Field

• Main Authors: Eustachio Nettis (Author), Maddalena D'Erasmo (Author), Elisabetta Di Leo (Author), Gianfranco Calogiuri (Author), Vincenzo Montinaro (Author), Antonio Ferrannini (Author), Angelo Vacca (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leukotrienes (LTs) are potent biological proinflammatory mediators. LTC4, LTD4, and LTE4 are more frequently involved in chronic inflammatory responses and exert their actions binding to a cysteinyl-LT 1 (CysLT1) receptor and a cysteinyl-LT 2 (CysLT2) receptor. LTs receptor antagonists available for...