Resolvin D1 Suppresses H₂O₂-Induced Senescence in Fibroblasts by Inducing Autophagy through the miR-1299/ARG2/ARL1 Axis

• Main Authors: Hyun Ji Kim (Author), Boram Kim (Author), Hyung Jung Byun (Author), Lu Yu (Author), Tuan Minh Nguyen (Author), Thi Ha Nguyen (Author), Phuong Anh Do (Author), Eun Ji Kim (Author), Kyung Ah Cheong (Author), Kyung Sung Kim (Author), Hiệu Huy Phùng (Author), Mostafizur Rahman (Author), Ji Yun Jang (Author), Seung Bae Rho (Author), Gyeoung Jin Kang (Author), Mi Kyung Park (Author), Ho Lee (Author), Kyeong Lee (Author), Jungsook Cho (Author), Hyo Kyung Han (Author), Sang Geon Kim (Author), Ai Young Lee (Author), Chang Hoon Lee (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ARG2 has been reported to inhibit autophagy in vascular endothelial cells and keratinocytes. However, studies of its mechanism of action, its role in skin fibroblasts, and the possibility of promoting autophagy and inhibiting cellular senescence through ARG2 inhibition are lacking. We induced cellul...