Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active.

• Những tác giả chính: Kayla Glockzin (Tác giả), Thomas D Meek (Tác giả), Ardala Katzfuss (Tác giả)
• Định dạng: Sách
• Được phát hành: Public Library of Science (PLoS), 2022-02-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Human African Trypanosomiasis (HAT), also known as sleeping sickness, is a Neglected Tropical Disease endemic to 36 African countries, with approximately 70 million people currently at risk for infection. Current therapeutics are suboptimal due to toxicity, adverse side effects, and emerging resista...