Scaling Pharmacodynamics from Rats to Humans to Support Erythropoietin and Romiplostim Combination Therapy to Treat Erythropoietin-Resistant Anemia

Recombinant human erythropoietin (rHuEPO) is one of the most effective drugs for the treatment of anemia in patients with chronic kidney disease. However, EPO-resistance is an important contributor to the increased risk of adverse effects. We previously showed that EPO treatment could induce precurs...

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Main Authors: Xiaoqing Fan (Author), Wojciech Krzyzanski (Author), Dongyang Liu (Author), Raymond S. M. Wong (Author), Xiaoyu Yan (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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