Early detachment of neuromuscular junction proteins in ALS mice with SODG93A mutation

• Main Authors: Hisashi Narai (Author), Yasuhiro Manabe (Author), Makiko Nagai (Author), Isao Nagano (Author), Yasuyuki Ohta (Author), Tetsuro Murakami (Author), Yasushi Takehisa (Author), Tatsushi Kamiya (Author), Koji Abe (Author)
• Format: Book
• Published: MDPI AG, 2009-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The transgenic animals with mutant copper/zinc superoxide dismutase (SOD1) DNA develop paralytic motor neuron disease resembling human amyotrophic lateral sclerosis (ALS) patients and are commonly used as models for ALS. In the transgenic (Tg) mice with the G93A mutation of the human SOD1 gene (SOD1...