Surgical Primary Tumor Resection Reduces Accumulation of CD11b⁺ Myeloid Cells in the Lungs Augmenting the Efficacy of an Intranasal Cancer Vaccination against Secondary Lung Metastasis

• Main Authors: Michael Donkor (Author), Jamie Y. Choe (Author), Danielle Marie Reid (Author), Hope K. Fiadjoe (Author), Byron Quinn (Author), Amalendu Ranjan (Author), Mark Pulse (Author), Pankaj Chaudhary (Author), Riyaz Basha (Author), Harlan P. Jones (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A hallmark of effective cancer treatment is the prevention of tumor reoccurrence and metastasis to distal organs, which are responsible for most cancer deaths. However, primary tumor resection is expected to be curative as most solid tumors have been shown both experimentally and clinically to accel...