AT-752, a double prodrug of a guanosine nucleotide analog, inhibits yellow fever virus in a hamster model.

• Main Authors: Kai Lin (Author), Steven S Good (Author), Justin G Julander (Author), Abbie E Weight (Author), Adel Moussa (Author), Jean-Pierre Sommadossi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Yellow fever virus (YFV) is a zoonotic pathogen re-emerging in parts of the world, causing a viral hemorrhagic fever associated with high mortality rates. While an effective vaccine is available, having an effective antiviral against YFV is critical against unexpected outbreaks, or when vaccination...