Tumor-Suppressing STF cDNA 3 Overexpression Suppresses Renal Fibrosis by Alleviating Anoikis Resistance and Inhibiting the PI3K/Akt Pathway

Background: Myofibroblast (MF) activation is the key event of irreversible renal interstitial fibrosis. Anoikis resistance is the hallmark of active MFs, which is conferred by continuous activation of the phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/protein kinase B (Akt) pathway. Our previ...

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Main Authors: Fei Xiao (Author), Xinghong Liu (Author), Yan Chen (Author), Huanzi Dai (Author)
Format: Book
Published: Karger Publishers, 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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