Cx43 Inhibition Attenuates Sepsis-Induced Intestinal Injury via Downregulating ROS Transfer and the Activation of the JNK1/Sirt1/FoxO3a Signaling Pathway

Cx43 Inhibition Attenuates Sepsis-Induced Intestinal Injury via Downregulating ROS Transfer and the Activation of the JNK1/Sirt1/FoxO3a Signaling Pathway

Intestinal injury has long been considered to play a crucial role in the pathophysiology of sepsis and has even been characterized as the "motor" of it. Thus, we explored the effects of connexin43 (Cx43) on sepsis-induced intestinal injury in order to provide potential therapeutic strategi...

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Main Authors: Zhaowei Zou (Author), Bin Liu (Author), Lisi Zeng (Author), Xianzi Yang (Author), Renli Huang (Author), Cheng Wu (Author), Huijuan Zhu (Author), Yi Gao (Author), Dongdong Yuan (Author), Jinlong Yu (Author)
Format: Book
Published: Hindawi Limited, 2019-01-01T00:00:00Z.
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