Acyclovir-Loaded Chitosan Nanospheres from Nano-Emulsion Templating for the Topical Treatment of Herpesviruses Infections

• Main Authors: Manuela Donalisio (Author), Federica Leone (Author), Andrea Civra (Author), Rita Spagnolo (Author), Ozgen Ozer (Author), David Lembo (Author), Roberta Cavalli (Author)
• Format: Book
• Published: MDPI AG, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acyclovir is not a good candidate for passive permeation since its polarity and solubility limit is partitioning into the stratum corneum. This work aims to develop a new topical formulation for the acyclovir delivery. New chitosan nanospheres (NS) were prepared by a modified nano-emulsion template...