Poly(acrylic acid)/Poly(vinyl alcohol) Microarray Patches for Continuous Transdermal Delivery of Levodopa and Carbidopa: In Vitro and In Vivo Studies

• Main Authors: Yaocun Li (Author), Lalitkumar K. Vora (Author), Jiawen Wang (Author), Akmal Hidayat Bin Sabri (Author), Andrew Graham (Author), Helen O. McCarthy (Author), Ryan F. Donnelly (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Levodopa (LD) has been the most efficacious medication and the gold standard therapy for Parkinson's disease (PD) for decades. However, its long-term administration is usually associated with motor complications, which are believed to be the result of the fluctuating pharmacokinetics of LD foll...