Perinatal Characteristics and the Sensitization to Cow Milk, Egg Whites and Wheat in Children up to 3 Years of Age

Food sensitization in early life identifies children at risk of developing allergic diseases. We investigated the sensitization to cow milk (CM), egg whites, and wheat. Newborns and infants under 3 years of age with available specific immunoglobulin E (sIgE) data were identified. A retrospective sur...

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Main Authors: Hsin-Yu Chang (Author), Zon-Min Lee (Author), Ling-Sai Chang (Author), Wei-Ling Feng (Author), Yao-Hsu Yang (Author), Mei-C (Author)
Format: Book
Published: MDPI AG, 2023-05-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Hsin-Yu Chang  |e author 
700 1 0 |a Zon-Min Lee  |e author 
700 1 0 |a Ling-Sai Chang  |e author 
700 1 0 |a Wei-Ling Feng  |e author 
700 1 0 |a Yao-Hsu Yang  |e author 
700 1 0 |a Mei-C  |e author 
245 0 0 |a Perinatal Characteristics and the Sensitization to Cow Milk, Egg Whites and Wheat in Children up to 3 Years of Age 
260 |b MDPI AG,   |c 2023-05-01T00:00:00Z. 
500 |a 10.3390/children10050860 
500 |a 2227-9067 
520 |a Food sensitization in early life identifies children at risk of developing allergic diseases. We investigated the sensitization to cow milk (CM), egg whites, and wheat. Newborns and infants under 3 years of age with available specific immunoglobulin E (sIgE) data were identified. A retrospective survey was conducted using data from the Chang Gung Research Database. Perinatal characteristics, such as singleton or multiples in a single pregnancy, parity, meconium staining, maternal age, spontaneous delivery or cesarean section, meconium passage, weeks of gestation, birth length, body weight, head and chest circumferences, and season, were obtained. The data on sIgE were collected, and a logistic regression model was used to determine the odds of sensitization. Positive sIgE for CM and egg whites was more likely to occur in boys than in girls. Early-life egg white and wheat sensitization was associated with increased birth body length and weight. A multivariate analysis indicated an association between egg white sIgE positivity and logarithmic total IgE. Higher total IgE levels and younger age were associated with egg white sensitization, and elevated weight and length at birth were linked to food sensitization, particularly to egg whites and wheat. 
546 |a EN 
690 |a Chang Gung Research Database 
690 |a cow milk 
690 |a egg whites 
690 |a specific immunoglobulin E 
690 |a wheat 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Children, Vol 10, Iss 5, p 860 (2023) 
787 0 |n https://www.mdpi.com/2227-9067/10/5/860 
787 0 |n https://doaj.org/toc/2227-9067 
856 4 1 |u https://doaj.org/article/8eea31d2cc2c49b7a557065e8f80e4ea  |z Connect to this object online.