Efficacy-Based Perspective to Overcome Reduced Opioid Analgesia of Advanced Painful Diabetic Neuropathy in Rats

Efficacy-Based Perspective to Overcome Reduced Opioid Analgesia of Advanced Painful Diabetic Neuropathy in Rats

Reduction of the opioid analgesia in diabetic neuropathic pain (DNP) results from μ-opioid receptor (MOR) reserve reduction. Herein, we examined the antinociceptive and antiallodynic actions of a novel opioid agonist 14-O-methymorphine-6-O-sulfate (14-O-MeM6SU), fentanyl and morphine in rats with st...

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Main Authors: Mihály Balogh (Author), Ferenc Zádor (Author), Zoltán S. Zádori (Author), Mohammed Shaqura (Author), Kornél Király (Author), Amir Mohammadzadeh (Author), Bence Varga (Author), Bernadette Lázár (Author), Shaaban A. Mousa (Author), Sándor Hosztafi (Author), Pál Riba (Author), Sándor Benyhe (Author), Klára Gyires (Author), Michael Schäfer (Author), Susanna Fürst (Author), Mahmoud Al-Khrasani (Author)
Format: Book
Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
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