Case Report: Reactive Lymphohistiocytic Proliferation in Infant With a Novel Nonsense Variant of IL2RG Who Received BCG Vaccine

• Main Authors: Amal M. Yahya (Author), Suleiman Al-Hammadi (Author), Nidal O. AlHashaykeh (Author), Salwa S. Alkaabi (Author), Abdulghani S. Elomami (Author), Asia A. AlMulla (Author), Majed M. Alremeithi (Author), Rewan M. Kabbary (Author), Ranjit Vijayan (Author), Abdul-Kader Souid (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We present here a male young infant with X-linked severe combined immunodeficiency (MIM#300400) due to the novel nonsense variant of IL2RG (interleukin 2 receptor, gamma; MIM#308380), NM_000206.2(IL2RG):c.820_823dup p.Ser275Asnfs*29. He developed aggressive reactive lymphohistiocytic proliferation a...