An Acid-Sensitive Bone Targeting Delivery System Carrying Acacetin Prevents Osteoporosis in Ovariectomized Mice

• Main Authors: Xiaochen Sun (Author), Chenyu Song (Author), Chenxi Zhang (Author), Chunlei Xing (Author), Juan Lv (Author), Huihui Bian (Author), Nanning Lv (Author), Dagui Chen (Author), Xin Dong (Author), Mingming Liu (Author), Li Su (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One effective treatment for postmenopausal osteoporosis is to inhibit osteoclasts and subsequent bone resorption. In our study, we demonstrated that acacetin, a flavone with potential therapeutic effects in infections, cancers, and several metabolic disorders, inhibited osteoclast differentiation an...