Synthesis and Evaluation of Two Long-Acting SSTR2 Antagonists for Radionuclide Therapy of Neuroendocrine Tumors

Synthesis and Evaluation of Two Long-Acting SSTR2 Antagonists for Radionuclide Therapy of Neuroendocrine Tumors

Somatostatin receptor subtype 2 (SSTR2) has become an essential target for radionuclide therapy of neuroendocrine tumors (NETs). JR11 was introduced as a promising antagonist peptide to target SSTR2. However, due to its rapid blood clearance, a better pharmacokinetic profile is necessary for more ef...

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Main Authors: Sofia Koustoulidou (Author), Maryana Handula (Author), Corrina de Ridder (Author), Debra Stuurman (Author), Savanne Beekman (Author), Marion de Jong (Author), Julie Nonnekens (Author), Yann Seimbille (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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3rd Floor Main Library

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