Screening Bioactive Compounds of Siraitia grosvenorii by Immobilized β2-Adrenergic Receptor Chromatography and Druggability Evaluation

• Main Authors: Xiaoni Jia (Author), Jiajun Liu (Author), Baimei Shi (Author), Qi Liang (Author), Juan Gao (Author), Gangjun Feng (Author), Zhongman Chang (Author), Qian Li (Author), Xiaohong Zhang (Author), Jianbo Chen (Author), Xinfeng Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As the first and key step of traditional Chinese medicine (TCM)-guided drug development, lead discovery necessitates continuous exploration of new methodology for screening bioactive compounds from TCM. This work intends to establish a strategy for rapidly recognizing β2-adrenergic receptor (β2-AR)...