Proteolysis-targeting chimaeras (PROTACs) as pharmacological tools and therapeutic agents: advances and future challenges

• Main Authors: Chao Wang (Author), Yujing Zhang (Author), Tingting Zhang (Author), Lingyu Shi (Author), Zhongmin Geng (Author), Dongming Xing (Author)
• Format: Knjiga
• Izdano: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Proteolysis-targeting chimaeras (PROTACs) have been developed to be an emerging technology for targeted protein degradation and attracted the favour of academic institutions, large pharmaceutical enterprises, and biotechnology companies. The mechanism is based on the inhibition of protein function b...