Proteolysis-targeting chimaeras (PROTACs) as pharmacological tools and therapeutic agents: advances and future challenges
Proteolysis-targeting chimaeras (PROTACs) have been developed to be an emerging technology for targeted protein degradation and attracted the favour of academic institutions, large pharmaceutical enterprises, and biotechnology companies. The mechanism is based on the inhibition of protein function b...
Guardat en:
Autors principals: | Chao Wang (Autor), Yujing Zhang (Autor), Tingting Zhang (Autor), Lingyu Shi (Autor), Zhongmin Geng (Autor), Dongming Xing (Autor) |
---|---|
Format: | Llibre |
Publicat: |
Taylor & Francis Group,
2022-12-01T00:00:00Z.
|
Matèries: | |
Accés en línia: | Connect to this object online. |
Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|
Ítems similars
-
Recent advances in IAP-based PROTACs (SNIPERs) as potential therapeutic agents
per: Chao Wang, et al.
Publicat: (2022) -
Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug
per: BoRa Lee, et al.
Publicat: (2023) -
PROTACs for BRDs proteins in cancer therapy: a review
per: Chao Wang, et al.
Publicat: (2022) -
Cancer-Specific Delivery of Proteolysis-Targeting Chimeras (PROTACs) and Their Application to Cancer Immunotherapy
per: Yujeong Moon, et al.
Publicat: (2023) -
A Mechanistic Pharmacodynamic Modeling Framework for the Assessment and Optimization of Proteolysis Targeting Chimeras (PROTACs)
per: Robin Thomas Ulrich Haid, et al.
Publicat: (2023)