Inhibition of Membrane-Associated Catalase, Extracellular ROS/RNS Signaling and Aquaporin/H<sub>2</sub>O<sub>2</sub>-Mediated Intracellular Glutathione Depletion Cooperate during Apoptosis Induction in the Human Gastric Carcinoma Cell Line MKN-45
The human gastric carcinoma cell line MKN-45 is a prototype of bona fide tumor cells, as it is protected from the NADPH oxidase-1 (NOX-1)-driven HOCl- and nitric oxide (NO)/peroxynitrite apoptosis-inducing signaling pathways by a membrane-associated catalase. The use of inhibitors/scavengers shows t...
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MDPI AG,
2021-10-01T00:00:00Z.
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A1234.567 |
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