Exosome-Transported circRNA_0000253 Competitively Adsorbs MicroRNA-141-5p and Increases IDD

• Main Authors: Jian Song (Author), Zhen-Hao Chen (Author), Chao-Jun Zheng (Author), Ke-Han Song (Author), Guang-Yu Xu (Author), Shun Xu (Author), Fei Zou (Author), Xiao-Sheng Ma (Author), Hong-Li Wang (Author), Jian-Yuan Jiang (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pathogenesis of intervertebral disc degeneration (IDD) is complex, and a better understanding of IDD pathogenesis may provide a better method for the treatment of IDD. Exosomes are 40-100 nm nanosized vesicles that are released from many cell types into the extracellular space. We speculated tha...