Membrane fusogenic nanoparticle‐based HLA‐peptide‐addressing universal T cell receptor‐engineered T (HAUL TCR‐T) cell therapy in solid tumor

• Main Authors: Ruihan Xu (Author), Qin Wang (Author), Junmeng Zhu (Author), Yuncheng Bei (Author), Yanhong Chu (Author), Zhichen Sun (Author), Shiyao Du (Author), Shujuan Zhou (Author), Naiqing Ding (Author), Fanyan Meng (Author), Baorui Liu (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract T cell receptor‐engineered T (TCR‐T) cell therapy has demonstrated therapeutic effects in basic research and clinical trials for treating solid tumors. Due to the peptide‐dependent recognition and the human leukocyte antigen (HLA)‐restriction, TCR‐T cell therapy is generally custom designed...