Inhibition of Xanthine Oxidoreductase Enhances the Potential of Tyrosine Kinase Inhibitors against Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is characterized by the expression of the oncogenic kinase BCR-ABL. Although tyrosine kinase inhibitors (TKIs) against BCR-ABL represent the standard therapeutic option for CML, resistances to TKIs can be a serious problem. Thus, the search for novel therapeutic approa...

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Main Authors: Marta Romo-González (Author), Sara Moreno-Paz (Author), Violeta García-Hernández (Author), Fermín Sánchez-Guijo (Author), Ángel Hernández-Hernández (Author)
Formato: Livro
Publicado em: MDPI AG, 2020-01-01T00:00:00Z.
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