A novel agent enhances the chemotherapeutic efficacy of doxorubicin in MCF-7 breast cancer cells

• Main Authors: Liang Wang (Author), Judy Yuet-Wa Chan (Author), Xinhua Zhou (Author), Guozhen Cui (Author), Zhixiang Yan (Author), Li Wang (Author), Ru Yan (Author), Lijun Di (Author), Yuqiang Wang (Author), Maggie Pui-Man Hoi (Author), Luchen Shan (Author), Simon M Y Lee (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have previously demonstrated that DT-010, a novel conjugate of danshensu (DSS) and tetramethylpyrazine (TMP), displays antitumor effects in breast cancer cells both in vitro and in vivo. In the present study, we investigated whether DT-010 enhances the chemotherapeutic effect of doxorubicin (Dox)...