Synergistic effect of CD47 blockade in combination with cordycepin treatment against cancer

• Main Authors: Chen Feng (Author), Rongzhang Chen (Author), Weiwei Fang (Author), Xinran Gao (Author), Hanjie Ying (Author), Xiao Zheng (Author), Lujun Chen (Author), Jingting Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cordycepin is widely considered a direct tumor-suppressive agent. However, few studies have investigated as the effect of cordycepin therapy on the tumor microenvironment (TME). In our present study, we demonstrated that cordycepin could weaken the function of M1-like macrophages in the TME and also...