Lack of Autophagy Induction by Lithium Decreases Neuroprotective Effects in the Striatum of Aged Rats

• Hlavní autoři: Angelica Jardim Costa (Autor), Adolfo Garcia Erustes (Autor), Rita Sinigaglia (Autor), Carlos Eduardo Neves Girardi (Autor), Gustavo José da Silva Pereira (Autor), Rodrigo Portes Ureshino (Autor), Soraya Soubhi Smaili (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2021-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

The pharmacological modulation of autophagy is considered a promising neuroprotective strategy. While it has been postulated that lithium regulates this cellular process, the age-related effects have not been fully elucidated. Here, we evaluated lithium-mediated neuroprotective effects in young and...