Chronic administration of prebiotics and probiotics ameliorates pathophysiological hallmarks of Alzheimer's disease in a APP/PS1 transgenic mouse model

• Main Authors: Daniele Lana (Author), Chiara Traini (Author), Irene Bulli (Author), Giorgia Sarti (Author), Giada Magni (Author), Selene Attorre (Author), Maria Grazia Giovannini (Author), Maria Giuliana Vannucchi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The gut microbiota (MB), although one of the main producers of Aβ in the body, in physiological conditions contributes to the maintainance of a healthy brain. Dysbiosis, the dysbalance between Gram-negative and Gram-positive bacteria in the MB increases Aβ production, contributing to t...