Chronic administration of prebiotics and probiotics ameliorates pathophysiological hallmarks of Alzheimer's disease in a APP/PS1 transgenic mouse model

• Hlavní autoři: Daniele Lana (Autor), Chiara Traini (Autor), Irene Bulli (Autor), Giorgia Sarti (Autor), Giada Magni (Autor), Selene Attorre (Autor), Maria Grazia Giovannini (Autor), Maria Giuliana Vannucchi (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Introduction: The gut microbiota (MB), although one of the main producers of Aβ in the body, in physiological conditions contributes to the maintainance of a healthy brain. Dysbiosis, the dysbalance between Gram-negative and Gram-positive bacteria in the MB increases Aβ production, contributing to t...