The Human 2-Cys Peroxiredoxins form Widespread, Cysteine-Dependent- and Isoform-Specific Protein-Protein Interactions

• Main Authors: Loes van Dam (Author), Marc Pagès-Gallego (Author), Paulien E. Polderman (Author), Robert M. van Es (Author), Boudewijn M. T. Burgering (Author), Harmjan R. Vos (Author), Tobias B. Dansen (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Redox signaling is controlled by the reversible oxidation of cysteine thiols, a post-translational modification triggered by H₂O₂ acting as a second messenger. However, H₂O₂ actually reacts poorly with most c...