Use of a recombinant cysteine proteinase from Leishmania (Leishmania) infantum chagasi for the Immunotherapy of canine visceral Leishmaniasis.

• Main Authors: Josie Haydée Lima Ferreira (Author), Lucilene Dos Santos Silva (Author), Ieda Maria Longo-Maugéri (Author), Simone Katz (Author), Clara Lúcia Barbiéri (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: A recombinant cysteine proteinase from Leishmania (Leishmania) infantum chagasi (rLdccys1) was previously shown to induce protective immune responses against murine and canine visceral leishmaniasis. These findings encouraged us to use rLdccys1 in the immunotherapy of naturally infected...