AAV-aMTD-Parkin, a therapeutic gene delivery cargo, enhances motor and cognitive functions in Parkinson's and Alzheimer's diseases

• Main Authors: Seokwon Lee (Author), Mingu Kang (Author), Seungwoo Lee (Author), Sangsun Yoon (Author), Yeonjin Cho (Author), Dongjae Min (Author), Daye Ann (Author), Jisoo Shin (Author), Young-Ki Paik (Author), Daewoong Jo (Author)
• Formato: Livro
• Publicado em: Elsevier, 2024-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Neurodegenerative disorders, such as Parkinson's disease (PD) and Alzheimer's disease (AD), have a global prevalence and profoundly impact both motor and cognitive functions. Although adeno-associated virus (AAV)-based gene therapy has shown promise, its application for treating central ne...