<i>Bis</i>(Tryptophan) Amphiphiles Form Ion Conducting Pores and Enhance Antimicrobial Activity against Resistant Bacteria

• Główni autorzy: Mohit Patel (Autor), Saeedeh Negin (Autor), Joseph Meisel (Autor), Shanheng Yin (Autor), Michael Gokel (Autor), Hannah Gill (Autor), George Gokel (Autor)
• Format: Książka
• Wydane: MDPI AG, 2021-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The compounds referred to as <i>bis</i>(tryptophan)s (BTs) have shown activity as antimicrobials. The hypothesis that the activity of these novel amphiphiles results from insertion in bilayer membranes and transport of cations is supported by planar bilayer voltage-clamp studies reported...