Persistent HIV-1 transcription in CD4+ T cells from ART-suppressed individuals can originate from biologically competent proviruses

• Main Authors: M. Vignoles (Author), V. Andrade (Author), M. Noguera (Author), C. Brander (Author), C. Mavian (Author), M. Salemi (Author), R. Paredes (Author), M. Sharkey (Author), M. Stevenson (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HIV-1 is able to persist in the face of potent antiretroviral therapy (ART). A number of strategies are being explored to allow ART-free viral remission or viral eradication. In order to gauge the progress of these strategies, assays with which to measure viral reservoir size and activity are needed...