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siRNA Knockdown of RRM2 Effectively Suppressed Pancreatic Tumor Growth Alone or Synergistically with Doxorubicin

Pancreatic cancer is currently one of the deadliest of the solid malignancies, whose incidence and death rates are increasing consistently during the past 30 years. Ribonucleotide reductase (RR) is a rate-limiting enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides, whic...

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Main Authors: Shuquan Zheng (Author), Xiaoxia Wang (Author), Yu-Hua Weng (Author), Xingyu Jin (Author), Jia-Li Ji (Author), Liangxia Guo (Author), Bo Hu (Author), Nan Liu (Author), Qiang Cheng (Author), Jianqi Zhang (Author), Huicheng Bai (Author), Tongren Yang (Author), Xin-Hua Xia (Author), Hong-Yan Zhang (Author), Shan Gao (Author), Yuanyu Huang (Author)
Format: Book
Published: Elsevier, 2018-09-01T00:00:00Z.
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