Rapid and validated UHPLC method for simultaneous determination of sofosbuvir, ledipasvir and paracetamol as commonly repurposed drugs for COVID-19 treatment: application in spiked human plasma

Abstract Background Sofosbuvir/ledipasvir (SOF/LDV), a combination of antiviral drugs, has been recently repurposed for COVID-19 management, according to Food and Drug Administration approval. Paracetamol (PAR) identified as a first-line antipyretic for COVID-19 symptoms' management. The use of...

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Main Authors: Sherif Gamal (Author), Gehad G. Mohamed (Author), Said A. Salih (Author), Menna I. Ezzeldin (Author), Asmaa A. Mandour (Author)
Format: Book
Published: SpringerOpen, 2023-10-01T00:00:00Z.
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3rd Floor Main Library

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