Genomic reduction at TTC repeats in the bacterial genome of treated cases of Hansen's disease: A possible survival mechanism of Mycobacterium leprae

• Main Authors: Abu Hena Hasanoor Reja (Author), Abhishek De (Author), Pradip Kumar Patra (Author), Supratik Biswas (Author), Umesh Duttagupta (Author), Amrita Sil (Author), Nibir Biswas (Author), Surajita Bannerjee (Author), Aarti Sarda (Author), Basudev Bhattacharya (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Mycobacterium leprae has a small genome and a tendency of persisting as a very low-grade infection. The authors have shown earlier, that the changes in TTC repeats, in M. leprae genome may contribute to the restriction of the pathogenicity of the bacterium and its survival strategy in...