SARS-CoV-2 delta (B.1.617.2) spike protein adjuvanted with Alum-3M-052 enhances antibody production and neutralization ability

• Egile Nagusiak: Hong Huang (Egilea), Zhongcheng Zhou (Egilea), Xinxin Xiong (Egilea), Zhihai Liu (Egilea), Xiaoxue Zheng (Egilea), Qingli Quan (Egilea), Meixing Yu (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

BackgroundOptimizing adjuvant is one of the critical methods to improve the vaccine. 3M-052, a novel TLR7/8 agonist which was designed for slow dissemination at the injection site, has a potential as adjuvant, but its performance as a vaccine adjuvant for SARS-CoV-2 (B.1.617.2) spike protein has not...