Facioscapulohumeral dystrophy weakened sarcomeric contractility is mimicked in induced pluripotent stem cells‐derived innervated muscle fibres

• Main Authors: Camille Laberthonnière (Author), Elva‐Maria Novoa‐del‐Toro (Author), Mégane Delourme (Author), Raphaël Chevalier (Author), Natacha Broucqsault (Author), Kilian Mazaleyrat (Author), Nathalie Streichenberger (Author), Véronique Manel (Author), Rafaëlle Bernard (Author), Emmanuelle Salort Campana (Author), Shahram Attarian (Author), Karine Nguyen (Author), Jérôme D. Robin (Author), Anais Baudot (Author), Frédérique Magdinier (Author)
• Format: Book
• Published: Wiley, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Facioscapulohumeral dystrophy (FSHD) is a late‐onset autosomal dominant form of muscular dystrophy involving specific groups of muscles with variable weakness that precedes inflammatory response, fat infiltration, and muscle atrophy. As there is currently no cure for this disease...