Early molecular diagnosis of BRAF status drives the neurosurgical management in BRAF V600E-mutant pediatric low-grade gliomas: a case report

• Main Authors: Gianluca Piccolo (Author), Antonio Verrico (Author), Giovanni Morana (Author), Gianluca Piatelli (Author), Patrizia De Marco (Author), Valentina Iurilli (Author), Manila Antonelli (Author), Gabriele Gaggero (Author), Antonia Ramaglia (Author), Marco Crocco (Author), Samuele Caruggi (Author), Claudia Milanaccio (Author), Maria Luisa Garrè (Author), Marco Pavanello (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background To date, this is the only report showing with close and consecutive magnetic resonance images the extremely rapid response of two types of pediatric low-grade gliomas (PLGG) to vemurafenib and its impact on the surgical approach. Cases presentation We report two cases of symptoma...