Apoptosis status and proliferative activity in mucopolysaccharidosis type I mice tongue mucosa cells

• Main Authors: Juliana Noguti (Author), Vanessa Gonçalves Pereira (Author), Joice Marques Guilheiro (Author), Ana Maria Martins (Author), Vânia D'Almeida (Author), Daniel Araki Ribeiro (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Mucopolysaccharidosis type I (MPS I) is caused by a deficiency of alfa-iduronidase (IDUA), which leads to intralysosomal accumulation of glysosaminoglycans. Evidences point secondary events like oxidative stress on lysosomal storage diseases including MPS I. Patients with MPS I present a...