Multi-dimensional characterization of immunological profiles in small cell lung cancer uncovers clinically relevant immune subtypes with distinct prognoses and therapeutic vulnerabilities

• Main Authors: Lin Yang (Author), Zicheng Zhang (Author), Jiyan Dong (Author), Yibo Zhang (Author), Zijian Yang (Author), Yiying Guo (Author), Xujie Sun (Author), Junling Li (Author), Puyuan Xing (Author), Jianming Ying (Author), Meng Zhou (Author)
• Format: Book
• Published: Elsevier, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Small-cell lung cancer (SCLC) is generally considered a 'homogenous' disease, with little documented inter-tumor heterogeneity in treatment guidance or prognosis evaluation. The precise identification of clinically relevant molecular subtypes remains incomplete and their translation into c...