The decoy oligodeoxynucleotide against HIF-1α and STAT5 ameliorates atopic dermatitis-like mouse model

• Main Authors: Mi-Gyeong Gwon (Author), Jaechan Leem (Author), Hyun-Jin An (Author), Hyemin Gu (Author), Seongjae Bae (Author), Jong Hyun Kim (Author), Kwan-Kyu Park (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atopic dermatitis (AD) is a common inflammatory skin disease caused by an immune disorder. Mast cells are known to be activated and granulated to maintain an allergic reaction, including rhinitis, asthma, and AD. Although hypoxia-inducible factor-1 alpha (HIF-1α) and signal transducer and activator...