Integrated Phytochemical Analysis Based on UPLC-Q-TOF-MS/MS, Network Pharmacology, and Experiment Verification to Explore the Potential Mechanism of Platycodon grandiflorum for Chronic Bronchitis

• Main Authors: Yaling Deng (Author), Hongmin Ren (Author), Xianwen Ye (Author), Lanting Xia (Author), Minmin Liu (Author), Ying Liu (Author), Ming Yang (Author), Songhong Yang (Author), Xide Ye (Author), Jinlian Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and AimPlatycodon grandiflorum (PG) has been widely used for treating chronic bronchitis (CB). However, the material basis and underlying mechanism of action of PG against CB have not yet been elucidated.MethodsTo analyze the ingredients in PG, ultraperformance liquid chromatography-quadr...