Two monoclonal antibodies against glycoprotein Gn protect mice from Rift Valley Fever challenge by cooperative effects.

• Main Authors: Benjamin Gutjahr (Author), Markus Keller (Author), Melanie Rissmann (Author), Felicitas von Arnim (Author), Susanne Jäckel (Author), Sven Reiche (Author), Reiner Ulrich (Author), Martin H Groschup (Author), Martin Eiden (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rift Valley fever virus (RVFV) is a zoonotic arbovirus that causes severe disease in humans and ruminants. The infection is characterized by abortions in pregnant animals, high mortality in neonates as well as febrile illness in humans that develop in 1% of cases encephalitis or hemorrhagic fever. T...