The Synthesis, In Vitro Bio-Evaluation, and In Silico Molecular Docking Studies of Pyrazoline-Thiazole Hybrid Analogues as Promising Anti-α-Glucosidase and Anti-Urease Agents

• Main Authors: Yousaf Khan (Author), Shoaib Khan (Author), Rafaqat Hussain (Author), Aneela Maalik (Author), Wajid Rehman (Author), Mohamed W. Attwa (Author), Rafia Masood (Author), Hany W. Darwish (Author), Hazem A. Ghabbour (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present work, a concise library of benzothiazole-derived pyrazoline-based thiazole (<b>1</b>-<b>17</b>) was designed and synthesized by employing a multistep reaction strategy. The newly synthesized compounds were screened for their α-glucosidase and urease inhibitory...